Certain online casinos accept American Express as a payment method. These casinos also offer payout options in cryptocurrency or by bank wire. Additionally, they provide promotions that reward users of American Express cards, starting from the initial deposit.

Further details are available from the source, including a list of specific brands that meet these criteria. These brands are highlighted for their acceptance of American Express and their payout and promotion policies.

The source provides more information on the five brands that accept American Express and offer cryptocurrency or bank wire payouts, along with their promotional offers for card users.